The two mistakes that actually hurt
Editing records where the nameservers do not point
Entirely invisible. The changes save successfully, they simply have no effect, because a different company is answering the questions. Always establish where DNS is actually served from before changing anything.
Publishing a second SPF record
Adding a new sending service and creating a fresh SPF record alongside the existing one feels correct and is not: the standard permits exactly one, and two make it invalid. The result is mail quietly failing authentication, which usually shows up as messages landing in spam rather than as an error anyone sees.
Multiple senders belong in a single record, combined. If you are adding a newsletter tool or a booking system that sends on your behalf, that is the moment to check.